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Our recombinant cell line development process includes gene synthesis (option), reporter and/or expression vectors construction, DNA transfer, selection of positive clones, structural & functional characterizations of positive clones. Custom development of your recombinant cell line (Ion channel, GPCR, Kinase, Chromatin protein, ...) includes:
Animal tissues or whole embryos are commonly used to establish primary cell cultures (PBMC, fibroblasts, myocytes, hepatocytes, (pre)adipocytes, ....) for downstream assays and analysis.
Differenciated cells from induced pluripotent progenitors, with species-specific protein expression patterns, are reliable and homogenous tools for drug discovery and predictability of drug efficacy and drug toxicity. On the one hand, we offer several "ready to use" models and, on the other hand, we offer development of your custom model. |
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